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Formula-216™ Vitamin C Formula Development

Genetic Approach To Restoring Internal Vitamin C Synthesis


It was biochemist Irvwin Stone who wrote in 1979 this “genetic approach, in which the gene is repaired or replaced so it will be capable of directing the synthesis of the active enzyme (gulonolactone oxidase)… would be a convenient solution to the problem, but the present ‘state of art’ in genetic engineering is not capable of doing this. Perhaps another 50 years will see this accomplished. Humans would then be able to perform the endogenous synthesis of ascorbate, just like the other mammals.” (~Irwin Stone, Homo Sapiens Ascorbicus, Medical Hyphotheses, Volume 5, 711-722, 1979.)

Implanation of the GULO Gene into Fish Eggs Resulted in Offspring the Internally Produced Vitamin C, Showing This Is Possible in Man, But There Is No Scientific or Political Impetus to Replicate This in Humans


Transgenic Expression of L-Gulono-y-lactone oxidase in Medaka (Oryzias latipes), a teleost fish that lacks this enzyme necessary for L-ascorbic acid biosynthesis.

Transfer of the gene for L-gulono-y-lactone oxidase, the missing enzyme in L-ascorbic acid biosynthesis in scurvy-prone animals, into medaka fish was successfully done. The plasmid for GLO cDNA was microinjected into the cytoplasm of fertilized eggs. Four male fish having the transgene in their germs cells came to maturity, and progeny derived from one of the fish possessed L-gulono-y-lactone oxidase activity.

Biochemical & Biophysical Research Communications, Volume 223, Issue 3, 25 June 1996, Pages 650-653

Gene Mutation Occurs After Birth, Which Means It Can Be Edited


Researchers reported the blood level of vitamin C was 1.7 times greater in a fetus than its mother.

Formula-216™ Creation & Discovery


New nutraceutical blend of olive extract combined with vitamins C, D, zinc and resveratrol, features a key ingredient that has been shown to elevate and maintain vitamin C blood levels in preliminary human tests without reliance upon consumption of vitamin C-rich foods or dietary supplements. This revolutionary dietary supplement is said to restore the human body’s ability to internally produce vitamin C that was lost due to a gene mutation many generations ago in early human history. The creator and formulator of this dietary supplement is Bill Sardi.

Formula 216
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Bill Sardi

Nutraceutical formulator; health journalist at ResveratrolNews.com and Knowledgeofhealth.com, is the driving force and innovator behind ENCODE NUTRITION.